GynoPrep®

The thin-layer preparation for gynecological cytology with the FDA-certified Rovers ® Cervex-Brush ® Combi.

The Rovers ® Cervex-Brush ® Combi is a highly developed brush which enables an improved removal of endocervical cells if compared to conventionally used swab instruments.

Important scientific publication for the gynecologist:
Sampling with the Rovers ® Cervex-Brush ® Combi results in the collection of the same amount of squamous cells, but in a two to threefold harvest of endocervical cells. This leads to the detection of a higher viral load of oncogenic HPV and an increase in the number of detected abnormal smears.

Publication in Cytopathology 2006/17 p. 374-381
Improved endocervical sampling and HPV viral load detection by Cervex-Brush ® Combi
CE Depuydt *, IH Benoy, EJ Bailleul **, J. Vandepitte *, AJ Vereecken * and JJ Bogers ***

* Laboratory for Clinical Pathology (Labo RIATOL), Antwerp, Belgium, ** Department of Gynecology, Sint-Vincentius Ziekenhuis, Nortsel, Belgium and *** Laboratory of Cell and Tissue Research, Faculty of Medicine, University of Antwerp, Antwerp, Belgium

Advantages of the method:
» No cells are lost due to filtration or suction or other separation processes
» Inflammatory signs such as granulocytes, lymphocytes or histiocytes are deliberately not removed from the preparation, as they are often used to make a diagnosis. The tumor diathesis remains intact.
» Specific flora is often a crucial indicator of the presence of a more reactive or more of a dyplastic lesion and is therefore an important indicator both in terms of differential diagnosis and therapy
» Representative cross-section with all cell types, cell groups and inflammatory cells
» No 3D effect during screening, typical storage of the CK cell groups is retained
» Better morphology of the single cell, even cell distribution
» Faster diagnosis thanks to the defined 22mm x 15mm rectangle
» Residual material is available for further HPV examinations, for example
» All HPV tests possible (high-risk HPV DNA test possible)
» GynoPrep ® is also suitable for processing extragenital cell examinations.
» Improved cell removal through Rovers ® Cervex-Brush ® Combi, especially for IUD wearers
» Simple, effective and economical